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Cat. No. | Product Name | Target | Signaling Pathways |
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T35788 |
Orlistat Degradation Product (sodium salt)
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Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat . It is formed via hydrolytic and thermal degradation as well as digestion by human carboxyl ester lipase. | |||
T76139 | Cholesterol esterase | ||
胆固醇酯酶 (Cholesterol esterase) 是一种在肠道内将胆固醇酯水解为胆固醇和游离脂肪酸的酶。胆固醇在腺泡细胞中合成,储存在酶原颗粒中。胆固醇酯酶又称胆盐刺激脂肪酶、羧基酯脂肪酶,具有促进胆固醇吸收的作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T37067 |
9-hydroxy Stearic Acid
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HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
9-hydroxy Stearic Acid 是一种羟基脂肪酸,是9-PAHSA 的活性代谢物。9-hydroxy Stearic Acid 是由9-PAHSA 通过肝脏和胰腺的羧基酯脂肪酶形成的。9-hydroxy Stearic Acid (5 μM)抑制HT-29结肠癌细胞裂解物中组蛋白去乙酰化酶1 (HDAC1)的表达。3 .当浓度为100 μM.1时,可抑制HT-29细胞的增殖,并诱导细胞周期阻滞于G0/ g1期。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-03353 |
CEL Protein, Mouse, Recombinant (His)
1810036E18Rik,carboxyl ester lipase |
Mouse | Baculovirus Insect Cells |
CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL c... | |||
TMPY-03182 |
PLRP2 Protein, Human, Recombinant (His)
PLRP2,pancreatic lipase-related protein 2 |
Human | Baculovirus Insect Cells |
Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso... |